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What are Elevated HA Levels ?
Read about
Ha-Joint-Formula presented in simple easy to understand language |
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Hyaluronic Acid plays an important role in tissue
hydration, lubrication and cellular function. Hyaluronic acid has the natural
ability to hold water in the skin and provides essential moisture to bodily
processes. HA helps control cell migration and also activates the white blood
cells. It stimulates the immune system and helps reduce bacterial infections and
has been found to inhibit the growth of a variety of strains of bacteria. Most
of the research for hyaluronic acid has been done in the field of orthopedics,
eye surgery and cosmetic surgery. The most popular use of hyaluronic acid,
today, is as supplements to combat signs of aging such as wrinkles and as
therapy for certain joint ailments. Hyaluronic acid injections are increasingly
being used to treat osteoarthritis of the knees. When hyaluronic acid produced
by the body decreases with age, it leads to various complications with the most
common being physical signs of aging and joint pains.
Research has also shown that when the hyaluronic acid levels are high in the
body, it could lead to complications. Elevated HA levels can be seen in patients
with chronic liver disease. This occurs due to the decreased removal of HA from
the blood by damaged sinusoidal endothelial cells in the liver. Increased
production of hyaluronic acid and passage into circulation is often seen during
synovial inflammation and cartilage destruction in rheumatoid arthritis (RA).
Other conditions in which elevated hyaluronic acid levels resulting from growth
factor activity in connective tissue cells and synovial involvement have been
noted include advanced osteoarthritis (OA), progressive systemic sclerosis (PSS)
and systemic lupus erythematosus (SLE).
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A few reports of elevated HA levels in
other medical conditions such as sepsis, acute pancreatitis, and
severe pre-eclampsia and eclampsia have also been published in
scientific literature. Certain types of cancer have been associated
with elevated HA levels and these include non-small cell lung cancer,
pleural mesothelioma, breast cancer, and bladder cancer. Various
myeloproliferative disorders such as malignant lymphoma, myelofibrosis,
and multiple myeloma have also indicated the presence of elevated HA
levels. In addition, patients with chronic renal failure on long-term
dialysis have been shown to have elevated concentrations of HA.
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